Partnering with Sollice Biotech

Big news from Enantis

At In-Cosmetics Global 2026 in Paris, we announced a strategic distribution partnership with SOLLICE BIOTECH, bringing our technologies closer to real-world cosmetic applications.

We are proud to see our GF-STAB technology entering the market under the name RegeNova®- XF2.

This milestone reflects our long-term focus – translating advanced protein engineering into products that deliver real value beyond the lab.

Combining our expertise in protein engineering with Sollice Biotech’s capabilities in formulation and market deployment opens new opportunities for stabilized growth factors in modern dermocosmetics.

RegeNova®- XF2:
✔️ boosts collagen
✔️ activates fibroblasts
✔️ accelerates skin repair
✔️ improves firmness and elasticity
✔️ reduces visible signs of aging

We’re excited to see our technology reach new applications and become part of next-generation skincare solutions.

7th Hands-on Computational Enzyme Design Course

Enzyme course 2026

Would you like to delve deeper into protein engineering?

Loschmidt Laboratories together with Enantis organize an interactive online hands-on course exploring web-based tools suitable for mining new enzymes and engineering enzyme activity, specificity, enantioselectivity, stability, and solubility. To remain at the cutting edge of scientific advancements, we will also explore the applications of machine learning techniques and quantum computing in enzyme design.

On the last day (optional), we will provide knowledge and training on processing experimental kinetic data (NEW this year!)

You will have the chance to learn from the developers or experienced users of those tools and discuss the optimal ways to set-up calculations and adequately interpret the results. At the end of this 5-day course, you will be able to design different properties of proteins for your academic research or commercial applications on your own.

When: 9-13 February 2026

Where: online

Who: protein and metabolic engineers with no prior experience in computer modeling and bioinformatics. Experts willing to broaden their current computational protein design toolbox will also benefit from this course. Doctoral students, postdocs, and staff members from both academia and companies are welcome.

Interested? Sign up here:

https://loschmidt.chemi.muni.cz/academy/

We still have free slots with an early-bird discount (till the end of November). Do not miss the opportunity and apply now! 

Czech Innovation at Work: LOBEY Laboratories Launches Growth Factor Serum Intense with Biotech Ingredient from Enantis

[Brno, Czech Republic] — A major milestone for Czech innovation in skincare: the newly launched Growth Factor Serum Intense from LOBEY features FGF2-STAB®, a cutting-edge ingredient developed by biotechnology company Enantis. This marks one of the first uses of advanced protein engineering from academic research in a mainstream dermocosmetic product — and the results speak for themselves.

Now available through LOBEY’s official e-shop, the serum offers a highly effective anti-ageing solution by combining natural actives with stabilized fibroblast growth factor FGF2, a powerful molecule long studied for its role in tissue regeneration and skin rejuvenation.

The Science Behind the Skincare
The standout ingredient — FGF2-STAB® — is a proprietary innovation from Enantis, a Czech biotech company born out of Masaryk University. Through advanced protein stabilization techniques, Enantis created a version of fibroblast growth factor that is significantly more stable, durable, and effective than its native form — unlocking new possibilities in cell-based research, regenerative medicine, and now: dermocosmetics.

Seeing our technology make its way into real-world skincare products is exciting. It’s a testament to the power of applied science and the growing potential of biotechnology in consumer markets,” says Marek Atanasčev, CEO of Enantis.

A Step Forward for Smart Cosmetics
Incorporating FGF2-STAB® into its Growth Factor Serum Intense, LOBEY has taken a bold step toward bridging the worlds of clean skincare and modern biotechnology. While LOBEY is known for its natural, gentle formulas, the addition of a scientifically validated, biotech-derived growth factor adds a new layer of performance — particularly in supporting collagen production, elasticity, and visible wrinkle reduction.

This isn’t about trends — it’s about function,” says Dr. Jan Herudek, Head of Applied Research at Enantis. “Wild type FGF2 is a well- known bioactive compound in regenerative dermatology. In FGF2-STAB® form, it finally becomes feasible for sustainable and long-lasting cosmetic use.

Local Science with Global Impact
The inclusion of FGF2-STAB® in a popular, publicly available product signals a larger trend: scientifically rigorous ingredients moving beyond the lab and into the everyday routines of consumers. This Czech-made growth factor, used by scientists worldwide in cell culture and regenerative research, is now powering skincare — and setting a new benchmark for biotech in cosmetics.

For consumers, it’s a sign that skincare is evolving. For Enantis, it’s another step toward making applied protein science a valuable part of people’s daily lives.

Webinar: Prediction of ligands, pockets and tunnels for enzymes

We’re thrilled to announce that our Senior Bioinformatician Ondrej Vavra from Enantis will be presenting at the 3D-BioInfo webinar tomorrow! 🎤

🔬 Topic: Prediction of Ligands, Pockets, and Tunnels for Enzymes
📅 Date: Tue 18 Feb 2025
⏰ Time: 4 pm GMT

Targeting the bottlenecks of enzyme tunnels is a powerful strategy in protein engineering, but identifying them across thousands of enzymes requires computational methods. In a recent study, we developed a pipeline combining automated structural analysis with an in-house machine-learning predictor to annotate protein pockets, as well as energy analysis of ligand binding and unbinding by CaverDock. This session will explore cutting-edge computational approaches.

Don’t miss this opportunity to dive into the world of 3D bioinformatics with us. Join the webinar and be part of the discussion!

📌 Register here: https://lnkd.in/e3MmsKgK

6th Hands-on Computational Enzyme Design Course

Would you like to delve deeper into protein engineering?

Loschmidt Laboratories together with Enantis organize an interactive hands-on course exploring web-based tools suitable for mining new enzymes and engineering enzyme activity, specificity, enantioselectivity, stability, and solubility. To remain at the cutting edge of scientific advancements, we will also explore the applications of machine learning techniques and quantum computing in enzyme design.

You will have the chance to learn from the developers or experienced users of those tools and discuss the optimal ways to set-up calculations and adequately interpret the results. At the end of this 4-day course, you will be able to design different properties of proteins for your academic research or commercial applications on your own.

When: 2-5 June 2025

Where: Brno, Czech Republic (on-site)

Interested? Sign up here:

https://loschmidt.chemi.muni.cz/academy/

We still have free slots with an early-bird discount (till the end of March). Do not miss the opportunity and apply now! 

Buy FGF2-STAB® – The Heat-Stable FGF2 from Enantis!

Discover the power of FGF2-STAB®, our innovative heat-stable fibroblast growth factor, now available for direct purchase in the Enantis e-shop. Designed for diverse and demanding applications, FGF2-STAB® ensures enhanced stability, reproducibility, and long-lasting activity.

At Enantis, we are proud to supply our heat-stable FGF2 to many of the world’s leading laboratory suppliers. Furthermore, we have licensed our heat-stable FGF technology to various companies, allowing them to market these groundbreaking products under their own brands.

Applications of heat stable FGF2-STAB®

  1. Regenerative Medicine
    • FGF2-STAB® promotes cell proliferation and tissue regeneration, making it invaluable in stem cell therapies, wound healing, and organoid development.
  2. Cosmetics
    • In skincare formulations, FGF2-STAB® enhances collagen production and cell renewal, delivering sustained and visible results for anti-aging products.
  3. Cultivated Meat
    • As a critical component in growth media, FGF2-STAB® supports muscle cell growth and differentiation, reducing media costs and enhancing scalability for lab-grown meat production.
  4. Tissue Engineering
    • With its unparalleled stability and activity, FGF2-STAB® is the ideal choice for creating engineered tissues used in research and therapeutic applications.
  5. Biomedical Research
    • Researchers rely on FGF2-STAB® for studies involving cell signaling, tissue repair, and protein stability, benefiting from its reproducibility and robust performance.

Available Now on the Enantis E-Shop

Ready to elevate your research or product development? FGF2-STAB® is now available for purchase on the Enantis E-shop. With user-friendly access and detailed product descriptions, the e-shop simplifies the ordering process for scientists, researchers, and industry professionals alike.

Enantis Progresses Development of FGF10-STAB to Address Severe Respiratory Conditions

Biotechnology pioneer Enantis is advancing the development of FGF10-STAB, a hyper-stable fibroblast growth factor, to provide innovative treatment solutions for patients with severe forms of Acute Respiratory Distress Syndrome (ARDS). ARDS is a life-threatening condition characterized by rapid onset of widespread inflammation in the lungs, often requiring mechanical ventilation. With a high mortality rate and no effective treatment available, there is an urgent need for new therapies that target the underlying causes and support recovery. 

FGF10-STAB stands out as a promising candidate due to its ability to promote tissue regeneration, reduce inflammation, and enhance alveolar repair. Its unique hyper-stable properties ensure prolonged activity and effectiveness, even under challenging conditions, making it an ideal candidate for addressing the needs of critically ill patients. The project focuses on determining the most effective delivery method—such as aerosol inhalation, endotracheal intubation, or carriers containing FGF10-STAB—and tailoring the solution for ventilated patients experiencing severe ARDS progression. 

Collaborating with members of the CZECRIN Pneumo platform, including doc. MUDr. Vladimír Koblížek, Ph.D. (FN Hradec Králové), prof. MUDr. Miloslav Marel, CSc. (FN Motol), MUDr. Petr Jakubec, Ph.D. (FN Olomouc), and MUDr. Ondřej Fibigr (FN Plzeň), Enantis is refining its approach by incorporating direct clinical feedback. These experts are providing essential guidance on formulating FGF10-STAB, identifying target patient groups, and designing experiments that demonstrate the solution’s efficacy convincingly. 

Initiated in November 2024 with its first meeting on November 26th, the project continues into 2025, with further consultations planned for Q1. The ultimate goal is to finalize a clinical formulation of FGF10-STAB and progress to First in Human clinical trials to validate its safety and efficacy. “ARDS is a devastating condition that leaves clinicians with few effective tools, and the urgency to innovate has never been greater,” said Marek Atanasčev, CEO of Enantis. “Our work on FGF10-STAB reflects our commitment to bridging groundbreaking research with real-world clinical needs. By collaborating with leading experts through the CZECRIN Pneumo platform, we aim to develop a therapy that can transform outcomes for ARDS patients and set a new standard of care.” 

This project underscores Enantis’ mission to combine scientific excellence with meaningful clinical applications. FGF10-STAB exemplifies the company’s dedication to addressing complex challenges in respiratory medicine and beyond.  

 

We are hiring!

We’re Hiring!

Enantis is looking for a passionate and driven Cellular Biologist to join our innovative biotech team in Brno!

If you’re excited about pushing the boundaries of science and contributing to the development of cutting-edge biotech solutions, we’d love to hear from you.

Take a look at the advert HERE

 

WEBINAR ALERT! Peptides Unveiled: Transforming the Future of Cosmetics

The world of cosmetics is evolving rapidly, and peptides are at the forefront of this transformation. These powerful molecules are changing the way we approach skincare, offering solutions that are scientifically advanced and results-driven. To delve deeper into this exciting field, Enantis invites you to an exclusive webinar: Peptides Unveiled: Transforming the Future of Cosmetics.

This is your opportunity to discover how peptides like FGF2-STAB®, a hyper-stable fibroblast growth factor, are revolutionizing beauty formulations and reshaping the cosmetics industry.

What to Expect in the Webinar

This interactive session is crafted specifically for professionals in the cosmetics industry, from formulators and product developers to R&D teams. Here’s what you’ll take away:

  1. Unlock the Power of FGF2-STAB®
    Learn how this cutting-edge growth factor enhances skin rejuvenation, combats signs of aging, and promotes healthy, radiant skin. Its hyper-stability ensures sustained bioactivity, making it a game-changer for skincare products.
  2. The Science Behind Beautiful Skin
    Discover the role peptides play in boosting collagen production, accelerating cellular repair, and delivering long-lasting, visible results. Gain insights into the biological mechanisms that make peptides indispensable for modern skincare formulations.
  3. Innovation for the Beauty Industry
    Explore how Enantis uses groundbreaking biotechnology to make high-performance peptides more effective, stable, and accessible. This session highlights how these advancements can empower your brand to create standout products in a competitive market.
  4. What’s Next in Skincare
    Stay ahead of the curve by exploring future trends and opportunities in peptide-based beauty solutions. From anti-aging innovations to targeted treatments, the possibilities are endless.

Why You Should Attend

In today’s fast-paced cosmetics industry, staying informed about emerging technologies is crucial. This webinar is perfect for:

  • Cosmetic formulators seeking to enhance their product offerings.
  • Product developers aiming to incorporate cutting-edge ingredients into their lines.
  • R&D teams looking to innovate and drive market trends.

By attending, you’ll gain actionable insights that can elevate your skincare formulations and position your brand as a leader in innovation.

Date: January 29th, 2025

Time: 4 PM CET

Join the Revolution and register for the webinar here Microsoft Virtual Events Powered by Teams

At Enantis, we believe in science-driven solutions that deliver real results. Our hyper-stable peptides, like FGF2-STAB®, represent the next generation of beauty innovations, combining efficacy with reliability.

Enantis Teams Up with Masaryk University’s Faculty of Pharmacy to Support Future Cosmetic Experts

We’re excited to announce a new partnership with the Faculty of Pharmacy at Masaryk University! This collaboration gives students from the bachelor’s program in “Cosmetic Products” the chance to gain hands-on experience through internships at Enantis.

“At Enantis, we’re passionate about supporting the next generation of professionals in cosmetics. This partnership lets students put their knowledge into practice while learning about cutting-edge biotech approaches,” said Marek Atanasčev, CEO of Enantis.

By working with us, students will get an inside look at how innovative cosmetic ingredients and technologies are developed, helping them connect their academic studies with real-world applications. This partnership is a step forward in bridging the gap between education and industry while nurturing fresh talent in the field.

The Faculty of Pharmacy is just as excited and believes this collaboration will give their students valuable experience and a solid foundation for their careers.

We can’t wait to welcome these students to Enantis, where their ideas and energy will not only help them grow but will also contribute to the future of the biotechnology research and cosmetics industry!